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Knee · Dr. Alexandre Journé · Lyon

Villonodular synovitis of the knee.

Identifying a rare condition of the synovial membrane and organizing its follow-up.

01 · Your journey

The current name

Pigmented villonodular synovitis belongs to the group of giant cell tenosynovial tumors. Usually benign, this proliferation of the synovium can nevertheless cause localized damage to the joint. It exists in both localized and diffuse forms.

02 · Your journey

Recurring swelling

Pain, stiffness, and recurring effusions, sometimes bloody without significant trauma, can lead to a diagnosis. An MRI clarifies the extent of the injury. Analysis of a tissue sample can confirm the nature of the lesion.

03 · Your Journey

A specialized strategy

Depending on the symptoms and extent, monitoring or excision of the lesion and affected synovium may be recommended, either arthroscopically or via open surgery. Diffuse, recurrent, or difficult-to-operate forms require a specialist, sometimes multidisciplinary, consultation. Targeted drug treatments may be considered in certain situations.

04 · Your Journey

Monitor for Recurrences

Prolonged follow-up is important, especially in diffuse forms. Clinical examinations and MRI scans are adapted to the progression of the condition.

Your questions.

Is it a simple inflammation?+

No. This is a specific condition of the synovium, which requires its own diagnosis and treatment strategy.

General information, which does not replace a consultation. Sources consulted on October 10, 2026:AAOS — Giant cell tenosynovial tumor ↗
Arranging your appointment

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in Lyon.

Consultations: 152 rue Vauban, Lyon 6th arrondissement.
Procedures at the Clinique du Parc Lyon.
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Practice in sector 2.
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